Fast, whole-heart, free-breathing 3D T2 mapping at 3T with application to myocardial edema imaging
نویسندگان
چکیده
Background Cardiac MRI (CMR) T2 mapping is a proven method for myocardial edema detection. However, the current approach requires multiple breath-holds and can take nearly 10-15 minutes to complete. Faster acquisitions could potentially improve patient comfort and costeffectiveness of CMR exams. the objecttive of this study is to develop and test a free-breathing, three-dimensional, cardiac MR approach which can yield fast, accurate, T2 maps of the whole left ventricle at 3T.
منابع مشابه
Fast, heart-rate independent, whole-heart, free-breathing, three-dimensional myocardial BOLD MRI at 3T with simultaneous 13N-ammonia PET validation in canines
Background Myocardial BOLD MRI is a non-contrast approach for examining myocardial perfusion. Although recent developments have shown promising technical advancements, current myocardial BOLD MR methods are still limited by: (a) poor spatial coverage; (b) imaging confounders; and (c) imaging artifacts, particularly at 3T. To address these limitations, we developed a heart-rate independent, free...
متن کاملFree-breathing myocardial T2 measurements at 1.5T
Introduction Myocardial T2 mapping is a valuable tool for tissue characterization and oedema visualization. For instance, it is used to detect early rejection of heart transplant [1]. T2 values are usually estimated by performing several black blood Fast Spin Echo (FSE) sequences with different Echo Times (TE), what requires multiple breath holds. Successive apneas could lead to misregistration...
متن کاملWhole-heart, free-breathing, three-dimensional myocardial BOLD MRI at 3T with simultaneous 13N-ammonia PET in canines
Background Myocardial BOLD MRI is an emerging non-contrast approach for the assessment of ischemic heart disease. However, current BOLD CMR methods (T2-weighted, T2*-weighted or bSSFP) are limited by poor spatial coverage and image artifacts (e.g. coil bias, B1 and B0 inhomogeneities). To address these limitations, we developed a fast, free breathing 3D T2 mapping technique at 3T that utilizes ...
متن کاملQuantitative free-breathing 3T T2-mapping of the heart designed for longitudinal studies
Background Recently, T2-weighted MRI for the characterization of edema after myocardial infarction has attracted considerable attention (Friedrich, NatRevCardiol2010). Furthermore, the recently proposed combination of bSSFP imaging and T2Prep for T2-mapping at 1.5T has enabled a rapid quantitative cardiac T2 estimation (Huang et al., MRM2007). However, the accuracy of this method may still be l...
متن کامل3D free-breathing late gadolinium enhancement 3T MRI: comparison with standard 2D Imaging
Background Clinical cardiovascular magnetic resonance imaging (CMR) is routinely performed during multiple breathholds in predefined 2D image orientations. 3D CMR is desirable, since it allows post-acquisition reformatting in any desired imaging plane. However, 3D CMR is hampered by long breath-hold duration, introducing patient discomfort and technical limitations. These limitations can be ove...
متن کامل